The 2-Minute Rule for megatomi.com
The 2-Minute Rule for megatomi.com
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Our new Apparent+ tissue clearing approach is the one process that delipidates samples with no alter in morphology and with nominal impact on structural integrity.
Megatome is a vibrating microtome meant to section a broad array of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With substantial blade vibrating frequency and minimized blade deflection, Megatome permits superior-throughput tissue sectioning with uniform surface profile, in addition to minimum tissue hurt and data decline.
Antibodies may possibly acquire months to diffuse by only some millimeters of tissue, that has a steep labeling gradient from area to Main.
Megatome is suitable for precision: the blade vibrates at a higher frequency and bigger amplitude vary than other microtomes, and encompasses a one of a kind deflection Command system.
SE works by using a rotational electrical discipline to disperse very electromobile molecules (like antibodies or surfactant micelles) all over a porous sample without the need of harming electrically billed structures throughout the tissue. This permits 2-4 working day clearing of intact organs,
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Megatome is usually a novel microtome that allows for prime-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with minimum tissue harm and knowledge loss.
eFLASH is often a quick tissue labeling procedure which allows for uniform complete-organ staining in 20 rounds of labeling.
Totally delipidate total mouse brains or comparably sized samples in just megatomi.com one working day with SmartBatch+, or in one 7 days with our passive clearing kit.
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Possibly download a launch or make a distribution zip as outlined over. Unzip the archive into a wished-for place.
Leverage the Obvious+ tissue clearing process, in conjunction with eFLASH and patented stochastic electrotransport systems, to swiftly clear and label entire organs. Critical highlights and features include:
Our novel Defend tissue preservation method kinds intramolecular bonds working with polyfunctional, versatile epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.